COLUMBIA LABORATORIES TO DISCUSS THIRD QUARTER 2009 FINANCIAL RESULTS

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ON NOVEMBER 5, 2009 CONFERENCE CALL

LIVINGSTON, NJ— October 22, 2009 —Columbia Laboratories, Inc. (Nasdaq: CBRX) will hold a conference call on November 5, 2009 to discuss financial results of the third quarter ended September 30, 2009. Robert S. Mills, president and chief executive officer, and Lawrence Gyenes, senior vice president, chief financial officer and treasurer of Columbia Laboratories, will host the call.

Access information

The teleconference replay will be available two hours after completion through Thursday, November 12, 2009 at 888-632-8973 (U.S. & Canada) or 201-499-0429. The replay passcode is 41415078. The archived webcast will be available for one year on the Company’s investor website,www.cbrxir.com, under "Events."

About Columbia Laboratories

Columbia Laboratories, Inc. is a specialty pharmaceutical company focused on developing and marketing products for the reproductive healthcare and endocrinology markets using its novel bioadhesive drug delivery technology. For more information, please visitwww.columbialabs.com.

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