Harris & Harris Group, Inc. (NASDAQ: TINY), an investor in transformative companies enabled by disruptive science, notes the announcement by portfolio company, Mersana Therapeutics, Inc., that it has achieved the second preclinical milestone in its collaboration with Endo Pharmaceuticals. In 2012, Mersana and Endo entered into a multi-target, oncology-focused partnership to develop next-generation Fleximer antibody-drug conjugates (ADCs).
The collaboration between Mersana and Endo leverages Mersana's proprietary conjugation technology, comprised of the Fleximer polymer and a broad array of customizable linker chemistries for attaching diverse, potent payloads to antibodies. Under the terms of the agreement, Mersana is responsible for conducting research and creating Fleximer-ADC development candidates with antibodies provided by Endo. The rights to these ADCs have been licensed to Endo in exchange for research funding, milestone payments and royalties on worldwide net sales of any resulting ADC products.
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