Partners extend existing alliance to develop novel cancer therapies / Joint investment of up to 30 million Euros for collaborative research in oncology over the next five years

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Leverkusen, February 4, 2014 – Bayer HealthCare and the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have agreed on a five-year strategic research alliance against cancer. The two partners have already been collaborating since 2009 with the aim of jointly developing novel therapeutic options for cancer patients. Bayer and the DKFZ will together invest up to 30 million Euros into their collaboration over the next five years to address the high medical need in cancer treatment and diagnosis.

“We are looking forward to another five years of fruitful collaboration with the DKFZ. Together we have already initiated twenty-eight projects and twelve projects have reached important milestones,” said Prof. Dr. Andreas Busch, Member of the Bayer HealthCare Executive Committee and Head of Global Drug Discovery. “The DKFZ’s scientific excellence as Germany’s largest biomedical research institute perfectly matches with Bayer’s proven drug discovery and development expertise. There is still a huge medical need in the treatment of a number of tumor types and cancer in general. This alliance demonstrates Bayer’s ongoing commitment to develop innovative therapies that can help patients suffering from cancer.”

“Increasingly, we can build on the excellent results of our basic research and transfer them to the clinic. For successful translation, we need strong partners: both in the clinic, where we can rely on the National Center for Tumor Diseases (NCT) in Heidelberg and on the German Consortium for Translational Cancer Research, and in industry. The strategic alliance with Bayer HealthCare over the past five years has been extremely successful. Together we are able to advance promising projects with the prospect of reaching the clinic and hopefully the patients. We are pleased to continue this alliance for another five years,” explained Prof. Dr. Dr. h.c. Wiestler, CEO of the German Cancer Research Center.

About the collaboration
The collaboration, which was started in 2009, aims at finding and exploiting molecules, mechanisms and models as new starting points for the development of innovative anticancer therapeutics. Furthermore, the German Cancer Research Center and Bayer are working to develop novel methods of diagnosis to monitor the individual course of disease and treatment progress, and help to predict the treatment success. Twenty-eight joint anti-cancer projects have been initiated so far, twenty of these are currently ongoing. To date, a total of twelve projects has already reached important milestones and moved on to the next phase of drug discovery namely compound screening to identify new potential drug candidates. Two of these projects have successfully passed compound screening and the project teams now envisage the identification of drug candidates for clinical testing. The German Cancer Research Center and Bayer jointly decide on the start, continuation and management of projects. To date, three projects have been exclusively licensed by Bayer.

Early in 2013, Bayer and the German Cancer Research Center further extended their strategic research alliance by also focusing on the field of immunotherapy. Scientists from both partners work together in a joint laboratory located at the National Center for Tumor Diseases (NCT) in Heidelberg.

Within the collaboration, the two partners have so far already invested more than 10 million Euros in their collaborative research. Over a period of another five years, the DKFZ and Bayer have agreed to further invest up to 6 million Euros per year, which would lead to an investment of up to 30 million Euros in collaborative oncology research projects.

About Oncology at Bayer
Bayer is committed to delivering science for a better life by advancing a portfolio of innovative treatments. The oncology franchise at Bayer now includes three oncology products and several other compounds in various stages of clinical development. Together, these products reflect the company’s approach to research, which prioritizes targets and pathways with the potential to impact the way that cancer is treated.

About the German Cancer Research Center
The German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) with 3,000 employees is the largest biomedical research institute in Germany. At DKFZ, more than 1,000 scientists are investigating the mechanisms of cancer, are identifying cancer risk factors and are trying to find new strategies to prevent people from getting cancer. They are developing novel approaches to make tumor diagnosis more precise and treatment of cancer patients more successful. In addition, the staff of the Cancer Information Service (KID) offers information about the widespread disease of cancer for patients, their families, and the general public. The Center is funded by the German Federal Ministry of Education and Research (90%) and the State of Baden-Wuerttemberg (10%) and is a member of the Helmholtz Association of National Research Centers.

About Bayer HealthCare
The Bayer Group is a global enterprise with core competencies in the fields of health care, agriculture and high-tech materials. Bayer HealthCare, a subgroup of Bayer AG with annual sales of EUR 18.6 billion (2012), is one of the world’s leading, innovative companies in the healthcare and medical products industry and is based in Leverkusen, Germany. The company combines the global activities of the Animal Health, Consumer Care, Medical Care and Pharmaceuticals divisions. Bayer HealthCare’s aim is to discover, develop, manufacture and market products that will improve human and animal health worldwide. Bayer HealthCare has a global workforce of 54,900 employees (Dec 31, 2012) and is represented in more than 100 countries. More information at www.healthcare.bayer.com.

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This release may contain forward-looking statements based on current assumptions and forecasts made by Bayer Group or subgroup management. Various known and unknown risks, uncertainties and other factors could lead to material differences between the actual future results, financial situation, development or performance of the company and the estimates given here. These factors include those discussed in Bayer’s public reports which are available on the Bayer website at www.bayer.com. The company assumes no liability whatsoever to update these forward-looking statements or to conform them to future events or developments.

News Source : Partners extend existing alliance to develop novel cancer therapies / Joint investment of up to 30 million Euros for collaborative research in oncology over the next five years

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