Researchers review risks, recommendations for weight gain management in midlife women

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ROCHESTER, Minn. – A review of the weight gain risks and challenges faced by women in midlife has led Mayo Clinic researchers to a series of recommendations for this patient population. The findings are published in this month's edition of Mayo Clinic Proceedings.

The average weight gain for women in their 50s and 60s is 1.5 pounds per year. For this group of women, much of that weight gain resides in the midsection. This type of fat is linked to a higher risk of cardiovascular disease, which is also the No. 1 cause of death for postmenopausal women. In addition to cardiovascular disease, central weight distribution puts this population at risk for abnormal glucose and lipid levels and high blood pressure.

“This population of women faces multiple challenges for maintaining a healthy weight,” says Ekta Kapoor, M.B.B.S., a Mayo Clinic endocrinologist and the study’s lead author. “Mood changes, sleep disturbances, hot flashes and the many other changes of menopause can disrupt what may have previously been a healthy lifestyle.”

Mayo Clinic Women’s Health researchers recommend primary care providers screen this population of women for being overweight, and establish behavioral interventions, including psychological support, regular physical activity and changes in eating habits.

For those who are early into menopause, hormone therapy may be a consideration to manage menopausal symptoms. Decreasing menopausal symptoms enables women to focus on healthy lifestyle changes.

With hormones and metabolism against them, postmenopausal women face some of the highest rates of obesity in the country.

In addition to the usual adverse consequences of obesity, postmenopausal women face some unique challenges posed by obesity, including worse hot flashes, sexual dysfunction and an increased cancer risk,” says Dr. Kapoor. “Targeting the lifestyle habits during midlife and beyond will help prevent further health consequences down the road. It’s never too late to start making healthy lifestyle choices.”

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About Mayo Clinic Proceedings
Mayo Clinic Proceedings is a monthly peer-reviewed medical journal that publishes original articles and reviews dealing with clinical and laboratory medicine, clinical research, basic science research and clinical epidemiology. Proceedings is sponsored by the Mayo Foundation for Medical Education and Research as part of its commitment to physician education. It publishes submissions from authors worldwide. The journal has been published for more than 80 years and has a circulation of 130,000. Articles are available online at www.mayoclinicproceedings.org.

About Mayo Clinic

Mayo Clinic is a nonprofit organization committed to medical research and education, and providing expert, comprehensive care to everyone who needs healing. For more information, visit mayoclinic.org/about-mayo-clinic or newsnetwork.mayoclinic.org.

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