SENOMYX TO WEBCAST CORPORATE PRESENTATION AT THEDEUTSCHE BANK 36TH ANNUAL HEALTHCARE CONFERENCE

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SAN DIEGO, CA – April 26, 2011 – Senomyx, Inc. (NASDAQ: SNMX), a leading company focused on using proprietary taste receptor technologies to discover and develop novel flavor ingredients for the food, beverage, and ingredient supply industries, announced today that Kent Snyder, the Company’s Chief Executive Officer, and John Poyhonen, President and Chief Operating Officer, will present a corporate overview on Tuesday, May 3, 2011 at 9:20 a.m. Eastern Time (6:20 a.m. Pacific Time) during the Deutsche Bank 36th Annual Healthcare Conference. The conference is taking place at the Intercontinental Boston in Boston, MA. During the presentation, Mr. Snyder and Mr. Poyhonen will discuss corporate developments including the Company’s pipeline of novel flavor ingredients and its business strategy.

To access the live presentation or a subsequent archived recording, please log onto Senomyx’s website athttp://www.senomyx.comand click on the “Investor Relations” tab. The archived webcast will be available for 30 days following the presentation. Please connect to Senomyx’s website prior to the start of the webcast to ensure adequate time to download any software that may be necessary

About Senomyx, Inc. (www.senomyx.com)

Senomyx is using proprietarytaste receptortechnologies to discover and developnovel flavor ingredients. These include new flavors such as Savory Flavors and Cooling Flavors, as well as flavor modulators such as Bitter Blockers and enhancers of Sweet and Salt tastes. Senomyx is also engaged in a new effort to discover and develop natural high-potency sweeteners. The Company hasproduct discovery and development collaborationswith global food, beverage, and ingredient supply companies, some of which are currently marketing products that contain Senomyx’s flavor ingredients. For more information, please visitwww.senomyx.com.

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