Babraham Institute ( Babraham Institute)

The Babraham Institute undertakes innovative, life sciences research to generate new knowledge of biological mechanisms underpinning lifelong health and wellbeing. Research focuses on signalling and genome regulation, particularly the interplay between the two, and how epigenetic signals can influence important physiological adaptations during the lifespan of an organism. By determining how the body reacts to dietary and environmental stimuli, and manages microbial and viral challenges, we aim to improve lifelong wellbeing and healthier ageing. From a strong base of discovery in cell signalling, internationally-leading groups are studying intracellular pathways to elucidate the mechanism of action of PI3-kinases, MAP kinases, small GTPases and calcium-mediated signalling in the immune, cardiovascular or nervous systems, and in processes like angiogenesis and during ageing. The key proteins identified often represent targets for therapeutic intervention, providing possibilities for further, translational, research.